Metallothionein-1L

Details

Name
Metallothionein-1L
Synonyms
  • Metallothionein-IL
  • MT-1L
  • MT-IL
Gene Name
MT1L
Organism
Humans
Amino acid sequence
>lcl|BSEQ0049465|Metallothionein-1L
MDPNCSCATGGSCSCASSCKCKECKCTSCKKSCCSCCPMGCAKCAQGCVCKGASEKCSCC
A
Number of residues
61
Molecular Weight
6062.11
Theoretical pI
Not Available
GO Classification
Functions
zinc ion binding
Processes
cellular response to zinc ion / negative regulation of growth
Components
cytoplasm / nucleus / perinuclear region of cytoplasm
General Function
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
Specific Function
Zinc ion binding
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Not Available
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDQ93083
UniProtKB Entry NameMT1L_HUMAN
HGNC IDHGNC:7404
General References
  1. Lambert E, Kille P, Swaminathan R: Cloning and sequencing a novel metallothionein I isoform expressed in human reticulocytes. FEBS Lett. 1996 Jul 1;389(2):210-2. [Article]

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB09130Copperapproved, investigationalnobinderDetails
DB12965Silverapproved, investigationalunknownbinderDetails