Epididymal sperm-binding protein 1
Details
- Name
- Epididymal sperm-binding protein 1
- Synonyms
- E12
- Epididymal secretory protein 12
- hE12
- Gene Name
- ELSPBP1
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0009392|Epididymal sperm-binding protein 1 MTRWSSYLLGWTTFLLYSYESSGGMHEECVFPFTYKGSVYFTCTHIHSLSPWCATRAVYN GQWKYCQSEDYPRCIFPFIYRGKAYNSCISQGSFLGSLWCSVTSVFDEKQQWKFCETNEY GGNSLRKPCIFPSIYRNNVVSDCMEDESNKLWCPTTENMDKDGKWSFCADTRISALVPGF PCHFPFNYKNKNYFNCTNEGSKENLVWCATSYNYDQDHTWVYC
- Number of residues
- 223
- Molecular Weight
- 26106.11
- Theoretical pI
- Not Available
- GO Classification
- Processessingle fertilizationComponentsextracellular region
- General Function
- Not Available
- Specific Function
- Binds to spermatozoa upon ejaculation and may play a role in sperm capacitation. Has phosphorylcholine-binding activity (By similarity).
- Pfam Domain Function
- fn2 (PF00040)
- Transmembrane Regions
- Not Available
- Cellular Location
- Secreted
- Gene sequence
>lcl|BSEQ0017448|Epididymal sperm-binding protein 1 (ELSPBP1) ATGACCCGATGGTCCAGTTACCTGTTGGGATGGACAACCTTCCTTCTCTATTCCTATGAG TCAAGTGGAGGGATGCATGAGGAATGTGTCTTTCCTTTCACCTACAAGGGATCTGTTTAC TTCACTTGCACCCATATTCATAGCTTATCCCCTTGGTGTGCCACCAGAGCCGTGTACAAC GGCCAGTGGAAGTACTGCCAGAGTGAAGATTACCCACGCTGTATCTTCCCTTTCATCTAT CGAGGAAAGGCTTATAACAGCTGCATCTCCCAGGGCAGCTTCTTAGGCAGTCTGTGGTGC TCAGTCACCTCTGTCTTCGATGAGAAACAGCAGTGGAAATTCTGTGAAACGAATGAGTAT GGGGGAAATTCTCTCAGGAAGCCCTGCATCTTCCCCTCCATCTACAGAAATAATGTGGTC TCTGATTGCATGGAGGATGAAAGCAACAAGCTCTGGTGCCCAACCACAGAGAACATGGAT AAGGATGGAAAGTGGAGTTTCTGTGCCGACACCAGAATTTCCGCGTTGGTCCCTGGCTTT CCTTGTCACTTTCCGTTCAACTATAAAAACAAGAATTATTTTAACTGCACTAACGAAGGA TCAAAGGAGAACCTTGTGTGGTGTGCAACTTCTTACAACTACGACCAAGACCACACCTGG GTGTATTGCTGA
- Chromosome Location
- 19
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q96BH3 UniProtKB Entry Name ESPB1_HUMAN HGNC ID HGNC:14417 - General References
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- Ekhlasi-Hundrieser M, Schafer B, Philipp U, Kuiper H, Leeb T, Mehta M, Kirchhoff C, Topfer-Petersen E: Sperm-binding fibronectin type II-module proteins are genetically linked and functionally related. Gene. 2007 May 1;392(1-2):253-65. Epub 2007 Jan 20. [Article]