NimA-related protein

Details

Name

NimA-related protein

Synonyms

Not Available

Gene Name

Not Available

Organism

Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)

Amino acid sequence

>lcl|BSEQ0019403|NimA-related protein
MSDFYDPRERDPSVSRRPQNRQSDEWIRELLLRGTIARVATLWQGEDGAAFPFITPLAYA
YRPEQGDLVYHTNVVGRLRANAGQGHPATLEVSEIGQFLPSNSPLELSVQYRSVMVFGTA
RVLAGEDARAALTTLSERVFPGLKVGETTRPISEDDLKRTSVYSLSIDRWSGKENWAEQA
IQEEDWPALGPEWLG

Number of residues

195

Molecular Weight

21890.23

Theoretical pI

4.7

GO Classification

Functions

FMN binding / oxidoreductase activity

General Function

Oxidoreductase activity

Specific Function

Not Available

Pfam Domain Function

• Pyridox_ox_2 (PF12900)

Transmembrane Regions

Not Available

Cellular Location

Not Available

Gene sequence

>lcl|BSEQ0019404|NimA-related protein
GTGAGCGACTTCTACGACCCCCGCGAGCGCGACCCGAGTGTCAGCCGTCGCCCACAAAAT
CGCCAGTCCGACGAGTGGATTCGGGAACTGCTGCTGCGCGGCACGATTGCCCGTGTCGCC
ACCCTCTGGCAGGGCGAGGACGGCGCGGCCTTTCCCTTCATCACGCCGCTGGCCTACGCT
TACCGCCCCGAACAGGGCGACCTCGTGTACCACACCAACGTCGTGGGGCGGCTGCGGGCC
AATGCGGGGCAAGGGCACCCGGCCACACTGGAAGTCTCCGAAATCGGCCAGTTTCTGCCG
AGCAACTCGCCGCTCGAACTCAGCGTGCAGTACCGCAGCGTGATGGTCTTTGGCACGGCG
CGGGTGCTGGCGGGCGAGGATGCGCGCGCGGCCCTCACCACCCTCTCCGAGCGGGTGTTC
CCTGGTCTGAAAGTGGGGGAGACGACCCGGCCCATTTCCGAGGATGACCTCAAGCGCACC
AGCGTTTATAGCCTGTCCATTGACCGCTGGAGCGGCAAGGAAAACTGGGCCGAGCAGGCG
ATTCAGGAGGAGGACTGGCCGGCGCTGGGGCCGGAGTGGCTGGGGTAA

Chromosome Location

Not Available

Locus

Not Available

External Identifiers

Resource	Link
UniProtKB ID	Q9RW27
UniProtKB Entry Name	Q9RW27_DEIRA
GenBank Gene ID	AE000513

General References

1. Leiros HK, Kozielski-Stuhrmann S, Kapp U, Terradot L, Leonard GA, McSweeney SM: Structural basis of 5-nitroimidazole antibiotic resistance: the crystal structure of NimA from Deinococcus radiodurans. J Biol Chem. 2004 Dec 31;279(53):55840-9. Epub 2004 Oct 18. [Article]
2. Leiros HK, Tedesco C, McSweeney SM: High-resolution structure of the antibiotic resistance protein NimA from Deinococcus radiodurans. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Jun 1;64(Pt 6):442-7. doi: 10.1107/S1744309108009901. Epub 2008 May 16. [Article]
3. Leiros HK, Brandsdal BO, McSweeney SM: Biophysical characterization and mutational analysis of the antibiotic resistance protein NimA from Deinococcus radiodurans. Biochim Biophys Acta. 2010 Apr;1804(4):967-76. doi: 10.1016/j.bbapap.2010.01.010. Epub 2010 Jan 21. [Article]

Drug Relations

Drug Relations

DrugBank ID	Name	Drug group	Pharmacological action?	Actions	Details
DB04398	Lactic acid	approved, vet_approved	unknown		Details