Zinc transporter ZIP10
Details
- Name
- Zinc transporter ZIP10
- Synonyms
- KIAA1265
- Solute carrier family 39 member 10
- ZIP-10
- ZIP10
- Zrt- and Irt-like protein 10
- Gene Name
- SLC39A10
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0052331|Zinc transporter ZIP10 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML PEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVFDIQF
- Number of residues
- 831
- Molecular Weight
- 94131.47
- Theoretical pI
- Not Available
- GO Classification
- Functionszinc ion transmembrane transporter activityProcessescellular zinc ion homeostasis / negative regulation of B cell apoptotic process / positive regulation of B cell proliferation / positive regulation of B cell receptor signaling pathway / positive regulation of protein tyrosine phosphatase activity / zinc ion import across plasma membraneComponentscell / integral component of plasma membrane
- General Function
- May act as a zinc-influx transporter.
- Specific Function
- Zinc ion transmembrane transporter activity
- Pfam Domain Function
- Zip (PF02535)
- Transmembrane Regions
- 411-431 438-458 495-515 687-707 732-752 759-779 801-821
- Cellular Location
- Membrane
- Gene sequence
>lcl|BSEQ0052332|Zinc transporter ZIP10 (SLC39A10) ATGAAGGTACATATGCACACAAAATTTTGCCTCATTTGTTTGCTGACATTTATTTTTCAT CATTGCAACCATTGCCATGAAGAACATGACCATGGCCCTGAAGCGCTTCACAGACAGCAT CGTGGAATGACAGAATTGGAGCCAAGCAAATTTTCAAAGCAAGCTGCTGAAAATGAAAAA AAATACTATATTGAAAAACTTTTTGAGCGTTATGGTGAAAATGGAAGATTATCCTTTTTT GGTTTGGAGAAACTTTTAACAAACTTGGGCCTTGGAGAGAGAAAAGTAGTTGAGATTAAT CATGAGGATCTTGGCCACGATCATGTTTCTCATTTAGATATTTTGGCAGTTCAAGAGGGA AAGCATTTTCACTCACATAACCACCAGCATTCCCATAATCATTTAAATTCAGAAAATCAA ACTGTGACCAGTGTATCCACAAAAAGAAACCATAAATGTGATCCAGAGAAAGAGACAGTT GAAGTGTCTGTAAAATCTGATGATAAACATATGCATGACCATAATCACCGCCTACGTCAT CACCATCGTTTGCATCATCATCTTGATCATAACAACACTCACCATTTTCATAATGATTCC ATTACTCCCAGTGAGCGTGGGGAGCCTAGCAATGAACCTTCAACAGAGACCAATAAAACC CAGGAACAATCTGATGTTAAACTACCGAAAGGAAAGAGGAAGAAAAAAGGGAGGAAAAGT AATGAAAATTCTGAGGTTATTACACCAGGTTTTCCCCCTAACCATGATCAGGGTGAACAG TATGAGCATAATCGGGTCCACAAACCTGATCGTGTACATAACCCAGGTCATTCTCATGTA CATCTTCCAGAACGTAATGGTCATGATCCTGGTCGTGGACACCAAGATCTTGATCCTGAT AATGAAGGTGAACTTCGACATACTAGAAAGAGAGAAGCACCACATGTTAAAAATAATGCA ATAATTTCTTTGAGAAAAGATCTAAATGAAGATGACCATCATCATGAATGTTTGAACGTC ACTCAGTTATTAAAATACTATGGTCATGGTGCCAACTCTCCCATCTCAACTGATTTATTT ACATACCTTTGCCCTGCATTGTTATATCAAATCGACAGCAGACTTTGTATTGAGCATTTT GACAAACTTTTAGTTGAAGATATAAATAAGGATAAAAACCTGGTTCCTGAAGATGAGGCA AATATAGGGGCATCAGCCTGGATTTGTGGTATCATTTCTATCACTGTCATTAGCCTGCTT TCCTTGCTAGGCGTGATCTTGGTTCCTATCATTAACCAAGGATGCTTCAAATTCCTTCTT ACATTCCTTGTTGCATTAGCTGTAGGAACAATGAGTGGAGACGCCCTTCTTCATCTACTG CCCCATTCTCAGGGTGGACATGATCACAGTCACCAACATGCACATGGGCATGGACATTCT CATGGACATGAATCTAACAAGTTTTTGGAAGAATATGATGCTGTATTGAAAGGACTTGTT GCTCTAGGAGGCATTTACTTGCTATTTATCATTGAACACTGCATTAGAATGTTTAAGCAC TACAAACAACAAAGAGGAAAACAGAAATGGTTTATGAAACAGAACACAGAAGAATCAACT ATTGGAAGAAAGCTTTCAGATCACAAGTTAAACAATACACCAGATTCTGACTGGCTTCAA CTCAAGCCTCTTGCCGGAACTGATGACTCGGTTGTTTCTGAAGATCGACTTAATGAAACT GAACTGACAGATTTAGAAGGCCAACAAGAATCCCCTCCTAAAAATTACCTTTGTATAGAA GAGGAGAAAATCATAGACCATTCTCACAGTGATGGATTACATACCATTCATGAGCATGAT CTCCATGCTGCTGCACATAACCACCACGGCGAGAACAAAACTGTGCTGAGGAAGCATAAT CACCAGTGGCACCACAAGCATTCTCATCATTCCCATGGCCCCTGTCATTCTGGATCCGAT CTGAAAGAAACAGGAATAGCTAATATAGCCTGGATGGTGATCATGGGGGATGGCATCCAC AACTTCAGTGATGGGCTCGCAATTGGTGCAGCTTTCAGTGCTGGATTGACAGGAGGAATC AGTACTTCTATAGCCGTCTTCTGTCATGAACTGCCACATGAATTAGGAGATTTTGCAGTT CTTCTTAAAGCAGGCATGACTGTAAAGCAAGCAATTGTATACAACCTCCTCTCTGCCATG ATGGCTTACATAGGCATGCTCATAGGCACAGCTGTTGGTCAGTATGCCAATAACATCACA CTTTGGATCTTTGCAGTCACTGCAGGCATGTTCCTCTATGTAGCCTTGGTGGATATGCTT CCAGAAATGTTGCATGGTGATGGTGACAATGAAGAACATGGCTTTTGTCCTGTGGGGCAA TTCATCCTTCAGAATTTAGGATTGCTCTTTGGATTTGCCATTATGCTGGTGATTGCCCTC TATGAAGATAAAATTGTGTTTGACATCCAGTTTTGA
- Chromosome Location
- 2
- Locus
- 2q32.3
- External Identifiers
Resource Link UniProtKB ID Q9ULF5 UniProtKB Entry Name S39AA_HUMAN HGNC ID HGNC:20861 - General References
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