5-methyltetrahydrofolate S-homocysteine methyltransferase
Details
- Name
- 5-methyltetrahydrofolate S-homocysteine methyltransferase
- Synonyms
- 5-methyltetrahydrofolate--homocysteine methyltransferase
- Gene Name
- Not Available
- Organism
- Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
- Amino acid sequence
>lcl|BSEQ0020680|5-methyltetrahydrofolate S-homocysteine methyltransferase MRNRREVSKLLSERVLLLDGAYGTEFMKYGYDDLPEELNIKAPDVVLKVHRSYIESGSDV ILTNTFGATRMKLRKHGLEDKLDPIVRNAVRIARRAAGEKLVFGDIGPTGELPYPLGSTL FEEFYENFRETVEIMVEEGVDGIIFETFSDILELKAAVLAAREVSRDVFLIAHMTFDEKG RSLTGTDPANFAITFDELDIDALGINCSLGPEEILPIFQELSQYTDKFLVVEPNAGKPIV ENGKTVYPLKPHDFAVHIDSYYELGVNIFGGCCGTTPEHVKLFRKVLGNRKPLQRKKKRI FAVSSPSKLVTFDHFVVIGERINPAGRKKLWAEMQKGNEEIVIKEAKTQVEKGAEVLDVN FGIESQIDVRYVEKIVQTLPYVSNVPLSLDIQNVDLTERALRAYPGRSLFNSAKVDEEEL EMKINLLKKYGGTLIVLLMGKDVPKSFEERKEYFEKALKILERHDFSDRVIFDPGVLPLG AEGKPVEVLKTIEFISSKGFNTTVGLSNLSFGLPDRSYYNTAFLVLGISKGLSSAIMNPL DETLMKTLNATLVILEKKELPRAEVKEEKLVEIILSGNRSELEKLVEDFLKEKDPLSVIE EHLRPAMERIGELYDKGKIFLPQLILAAQTVKPVFDKLTSMLPSDSQGETFVIATVKGDV HDIGKNIVASVIRSSGYRVVDLGKDVDTSEIVEAVEKERPVALGLSAMMTTTVGRIKEVV EKLKEKNLKIPVIVGGASLNEKLAKELGADYYAKNASEAVKILKSLGR
- Number of residues
- 768
- Molecular Weight
- 85703.315
- Theoretical pI
- 5.5
- GO Classification
- Functionscobalamin binding / metal ion binding / methionine synthase activityProcessespteridine-containing compound metabolic process
- General Function
- Methionine synthase activity
- Specific Function
- Not Available
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0020681|5-methyltetrahydrofolate S-homocysteine methyltransferase ATGAGAAACAGACGTGAGGTTTCAAAATTGCTTTCAGAAAGGGTGTTGCTCCTAGATGGT GCTTACGGAACAGAATTCATGAAGTACGGATACGATGACCTTCCCGAAGAGCTGAATATA AAAGCACCCGATGTGGTGCTGAAAGTTCATAGAAGTTACATAGAGAGTGGATCGGATGTC ATTCTGACGAACACGTTCGGTGCCACAAGGATGAAACTGAGAAAACACGGGCTGGAGGAC AAACTGGACCCTATTGTGAGAAACGCTGTGAGAATCGCAAGAAGAGCAGCTGGAGAAAAG CTTGTTTTTGGAGATATCGGACCGACGGGAGAACTTCCCTATCCACTCGGAAGCACTTTG TTCGAGGAATTCTACGAGAACTTCAGAGAAACCGTGGAGATAATGGTCGAAGAAGGTGTG GACGGAATCATCTTTGAGACGTTCTCGGACATTCTCGAGCTGAAAGCCGCTGTGCTTGCG GCAAGGGAAGTATCCCGGGATGTTTTCCTGATTGCCCACATGACATTCGATGAGAAGGGA AGAAGTCTTACAGGGACAGATCCCGCAAACTTTGCCATCACGTTCGATGAACTGGATATC GATGCCCTCGGTATAAACTGTTCACTCGGGCCCGAAGAGATCCTTCCCATTTTTCAGGAA CTGTCCCAGTACACAGACAAGTTTCTCGTAGTGGAACCTAACGCGGGAAAGCCCATCGTG GAGAACGGGAAAACTGTGTATCCTTTAAAACCACACGATTTTGCCGTTCACATAGACTCC TATTACGAACTCGGCGTGAACATATTCGGAGGCTGCTGCGGAACCACCCCTGAACACGTG AAGCTCTTCAGAAAAGTTCTCGGAAACAGAAAGCCTCTTCAAAGAAAGAAAAAGAGAATA TTCGCTGTCTCTTCTCCTTCAAAACTCGTGACGTTCGATCATTTCGTCGTCATAGGAGAG AGGATAAACCCGGCAGGTAGAAAGAAGCTATGGGCGGAGATGCAGAAAGGAAACGAAGAA ATTGTGATCAAGGAAGCGAAAACACAGGTGGAAAAAGGCGCGGAAGTGCTTGATGTGAAC TTCGGGATAGAATCTCAGATAGACGTACGATACGTGGAAAAGATCGTTCAAACACTTCCG TATGTTTCGAACGTTCCTCTTTCCTTGGACATCCAGAACGTCGACCTCACAGAGAGAGCG CTCAGAGCCTATCCGGGAAGATCTCTTTTCAACTCGGCCAAGGTGGATGAAGAAGAACTC GAAATGAAAATAAACCTGTTGAAGAAATACGGAGGTACACTCATCGTACTATTGATGGGA AAAGACGTTCCAAAAAGCTTCGAAGAGAGAAAAGAGTACTTCGAAAAGGCTTTGAAAATC CTGGAGAGACACGATTTCTCAGACAGGGTGATCTTCGATCCAGGAGTTCTGCCCCTCGGT GCAGAAGGAAAACCGGTAGAAGTACTGAAGACCATAGAATTCATCTCAAGCAAGGGTTTC AACACAACTGTTGGTCTTTCCAACCTGTCTTTCGGACTTCCTGACAGAAGTTATTACAAC ACCGCTTTTCTCGTTCTTGGAATATCTAAAGGCCTGAGCTCTGCCATCATGAATCCCCTC GACGAAACACTAATGAAGACCTTGAACGCTACACTTGTGATACTTGAAAAGAAGGAACTT CCCAGGGCTGAAGTGAAGGAAGAAAAACTGGTTGAAATCATACTCTCCGGGAACCGGTCG GAACTCGAGAAGCTTGTGGAGGATTTTCTGAAGGAAAAAGATCCTCTTTCCGTCATAGAA GAACACCTGAGGCCAGCGATGGAACGTATTGGAGAACTCTACGATAAGGGAAAGATCTTT CTGCCGCAACTCATCCTCGCCGCTCAAACGGTGAAACCCGTGTTCGACAAACTGACATCG ATGCTTCCATCAGACAGTCAGGGTGAAACGTTCGTCATTGCAACAGTCAAGGGTGATGTG CACGACATAGGAAAGAACATAGTGGCATCTGTCATCAGAAGCAGCGGGTACCGCGTGGTG GACCTTGGAAAAGACGTGGACACATCGGAAATAGTGGAAGCCGTGGAAAAAGAAAGACCC GTTGCACTCGGTCTGTCTGCAATGATGACAACCACCGTCGGCAGAATAAAGGAAGTTGTG GAAAAGCTCAAAGAAAAGAACCTGAAAATCCCTGTCATAGTGGGTGGTGCTTCCCTGAAC GAAAAACTAGCAAAAGAGCTTGGAGCGGACTATTACGCAAAGAATGCTTCCGAAGCGGTA AAAATATTGAAATCTCTTGGGAGATGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q9WYA5 UniProtKB Entry Name Q9WYA5_THEMA GenBank Gene ID AE000512 - General References
- Nelson KE, Clayton RA, Gill SR, Gwinn ML, Dodson RJ, Haft DH, Hickey EK, Peterson JD, Nelson WC, Ketchum KA, McDonald L, Utterback TR, Malek JA, Linher KD, Garrett MM, Stewart AM, Cotton MD, Pratt MS, Phillips CA, Richardson D, Heidelberg J, Sutton GG, Fleischmann RD, Eisen JA, White O, Salzberg SL, Smith HO, Venter JC, Fraser CM: Evidence for lateral gene transfer between Archaea and bacteria from genome sequence of Thermotoga maritima. Nature. 1999 May 27;399(6734):323-9. [Article]
- Latif H, Lerman JA, Portnoy VA, Tarasova Y, Nagarajan H, Schrimpe-Rutledge AC, Smith RD, Adkins JN, Lee DH, Qiu Y, Zengler K: The genome organization of Thermotoga maritima reflects its lifestyle. PLoS Genet. 2013 Apr;9(4):e1003485. doi: 10.1371/journal.pgen.1003485. Epub 2013 Apr 25. [Article]