NAV

Sulfametomidine

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Sulfametomidine
DrugBank Accession Number
DB13485
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
3D
Similar Structures
Weight
Average: 294.33
Monoisotopic: 294.078661501
Chemical Formula
C12H14N4O3S
Synonyms
  • Sulfametomidine
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
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AcarboseThe therapeutic efficacy of Acarbose can be increased when used in combination with Sulfametomidine.
AcetohexamideThe therapeutic efficacy of Acetohexamide can be increased when used in combination with Sulfametomidine.
AlbiglutideThe therapeutic efficacy of Albiglutide can be increased when used in combination with Sulfametomidine.
AlogliptinThe therapeutic efficacy of Alogliptin can be increased when used in combination with Sulfametomidine.
BenzylpenicillinSulfametomidine may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level.
Food Interactions
Not Available

Categories

ATC Codes
J01ED03 — Sulfametomidine
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as aminobenzenesulfonamides. These are organic compounds containing a benzenesulfonamide moiety with an amine group attached to the benzene ring.
Kingdom
Organic compounds
Super Class
Benzenoids
Class
Benzene and substituted derivatives
Sub Class
Benzenesulfonamides
Direct Parent
Aminobenzenesulfonamides
Alternative Parents
Benzenesulfonyl compounds / Aniline and substituted anilines / Alkyl aryl ethers / Pyrimidines and pyrimidine derivatives / Organosulfonamides / Imidolactams / Heteroaromatic compounds / Aminosulfonyl compounds / Azacyclic compounds / Primary amines
show 3 more
Substituents
Alkyl aryl ether / Amine / Aminobenzenesulfonamide / Aminosulfonyl compound / Aniline or substituted anilines / Aromatic heteromonocyclic compound / Azacycle / Benzenesulfonyl group / Ether / Heteroaromatic compound
show 16 more
Molecular Framework
Aromatic heteromonocyclic compounds
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
940ZL3AHKB
CAS number
3772-76-7
InChI Key
QKLSCPPJEVXONT-UHFFFAOYSA-N
InChI
InChI=1S/C12H14N4O3S/c1-8-14-11(7-12(15-8)19-2)16-20(17,18)10-5-3-9(13)4-6-10/h3-7H,13H2,1-2H3,(H,14,15,16)
IUPAC Name
4-amino-N-(6-methoxy-2-methylpyrimidin-4-yl)benzene-1-sulfonamide
SMILES
COC1=NC(C)=NC(NS(=O)(=O)C2=CC=C(N)C=C2)=C1

References

General References
Not Available
ChemSpider
18460
ChEBI
32163
ChEMBL
CHEMBL485940
ZINC
ZINC000000002098
Wikipedia
Sulfametomidine

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.26 mg/mLALOGPS
logP0.92ALOGPS
logP1.39Chemaxon
logS-3ALOGPS
pKa (Strongest Acidic)7.18Chemaxon
pKa (Strongest Basic)3.66Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count6Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area107.2 Å2Chemaxon
Rotatable Bond Count3Chemaxon
Refractivity75.97 m3·mol-1Chemaxon
Polarizability28.91 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-0a4i-0920000000-ec2197c6eaaf14b6fea1
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-0a4i-0920000000-49b4ca72b0385a237526
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-052f-0590000000-649cf8481b0aa452cbd8
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0a4i-0900000000-536997946a4770d36809
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-06dm-9510000000-fbc8d98f96954ca322b0
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-056v-4900000000-cec4f7952e4cf0983eb8
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-184.6635548
predicted
DarkChem Lite v0.1.0
[M-H]-169.8011
predicted
DeepCCS 1.0 (2019)
[M+H]+185.1293548
predicted
DarkChem Lite v0.1.0
[M+H]+172.1591
predicted
DeepCCS 1.0 (2019)
[M+Na]+184.9570548
predicted
DarkChem Lite v0.1.0
[M+Na]+178.25224
predicted
DeepCCS 1.0 (2019)

Drug created at June 23, 2017 20:42 / Updated at February 21, 2021 18:54