Ferric chloride

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Ferric chloride
DrugBank Accession Number
DB15536
Background

Not Available

Type
Small Molecule
Groups
Approved, Experimental
Structure
Weight
Average: 162.204
Monoisotopic: 160.841500254
Chemical Formula
Cl3Fe
Synonyms
  • Ferric chloride, anhydrous
  • Iron (III) chloride
  • Iron chloride
  • Iron perchloride

Pharmacology

Indication

Not Available

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Used in combination to treatTrace element deficiencyCombination Product in combination with: Sodium molybdate (DB14496), Manganese (DB06757), Sodium fluoride (DB09325), Zinc chloride (DB14533), Selenious acid (DB11127), Cupric Chloride (DB09131), Chromic chloride (DB09129), Potassium Iodide (DB06715)••••••••••••••••••••• ••••••••• •••••••••••
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
No interactions found.

Products

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Product Ingredients
IngredientUNIICASInChI Key
Ferric chloride hexahydrate0I2XIN602U10025-77-1NQXWGWZJXJUMQB-UHFFFAOYSA-K
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
ADDAMEL INFUSION NFerric chloride hexahydrate (5.4 mg) + Chromic chloride hexahydrate (53.3 mcg) + Cupric chloride dihydrate (3.4 mg) + Manganese chloride tetrahydrate (990 mcg) + Potassium Iodide (166 mcg) + Sodium selenite pentahydrate (105 mcg) + Sodium fluoride (2.1 mg) + Sodium molybdate dihydrate (48.5 mcg) + Zinc chloride (13.6 mg)Solution, concentrateIntravenousFRESENIUS KABI COLOMBIA S.A.S.2006-11-102009-05-08Colombia flag
ADDAMEL NFerric chloride hexahydrate (0.54 mg/ml) + Chromic chloride hexahydrate (5.33 mcg/ml) + Cupric chloride dihydrate (0.1 mg/ml) + Manganese chloride tetrahydrate (19.8 mcg/ml) + Potassium Iodide (16.6 mcg/ml) + Sodium selenite (17.3 mcg/ml) + Sodium fluoride (0.21 mg/ml) + Sodium molybdate dihydrate (4.85 mcg/ml) + Zinc chloride (1.05 mg/ml)Injection, solution, concentrateIntravenousFresenius Kabi Italia S.R.L.2014-07-082020-05-12Italy flag
ADDAMEL N FOR INFUSIONFerric chloride hexahydrate (0.54 mg/ml) + Chromic chloride hexahydrate (5.33 mcg/ml) + Cupric chloride dihydrate (0.34 mg/ml) + Manganese chloride tetrahydrate (99 mcg/ml) + Potassium Iodide (16.6 mcg/ml) + Sodium selenite (6.9 mcg/ml) + Sodium fluoride (0.21 mg/ml) + Sodium molybdate dihydrate (4.85 mcg/ml) + Zinc chloride (1.36 mg/ml)InjectionIntravenousFRESENIUS KABI (SINGAPORE) PTE LTD1992-01-31Not applicableSingapore flag
ADDAVEN CONCENTRATE FOR SOLUTION FOR INFUSIONFerric chloride hexahydrate (540 mcg/ml) + Chromic chloride hexahydrate (5.33 mcg/ml) + Cupric chloride dihydrate (102.3 mcg/ml) + Manganese chloride tetrahydrate (19.79 mcg/ml) + Potassium Iodide (16.6 mcg/ml) + Sodium selenite (17.29 mcg/ml) + Sodium fluoride (210 mcg/ml) + Sodium molybdate dihydrate (4.85 mcg/ml) + Zinc chloride (1050 mcg/ml)SolutionIntravenousFRESENIUS KABI (SINGAPORE) PTE LTD2017-07-24Not applicableSingapore flag
Addaven Konzentrat zur Herstellung einer InfusionslösungFerric chloride hexahydrate (0.54 mg/ml) + Chromic chloride hexahydrate (5.33 μg/ml) + Cupric chloride dihydrate (0.1 mg/ml) + Manganese chloride tetrahydrate (19.8 μg/ml) + Potassium Iodide (16.6 μg/ml) + Sodium selenite (17.3 μg/ml) + Sodium fluoride (0.21 mg/ml) + Sodium molybdate dihydrate (4.85 μg/ml) + Zinc chloride (1.05 mg/ml)Injection, solution, concentrateIntravenousFresenius Kabi Austria Gmb H2015-03-02Not applicableAustria flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Addamel NFerric chloride (0.11 mg/1mL) + Chromic chloride hexahydrate (1 ug/1mL) + Cuprous chloride (0.13 mg/1mL) + Manganese chloride tetrahydrate (0.027 mg/1mL) + Potassium Iodide (0.013 mg/1mL) + Sodium selenite (3.2 ug/1mL) + Sodium fluoride (0.095 mg/1mL) + Sodium molybdate dihydrate (1.9 ug/1mL) + Zinc chloride (0.65 mg/1mL)Injection, solutionIntravenousFresenius Kabi USA, LLC2013-05-072017-03-31US flag
ADDAMEL N 20 AMPULFerric chloride (5.4 mg/10mL) + Chromic chloride (53.3 mcg/10mL) + Cupric Chloride (3.4 mg/10mL) + Manganese chloride (990 mcg/10mL) + Potassium Iodide (166 mcg/10mL) + Sodium selenite (69 mcg/10mL) + Sodium fluoride (2.1 mg/10mL) + Sodium molybdate (48.5 mcg/10mL) + Zinc chloride (13.6 mg/10mL)Injection, solutionIntravenousFRESENİUS KABİ İLAÇ SAN. VE TİC. LTD. ŞTİ.2019-04-30Not applicableTurkey flag
ADDAVEN IV INFUZYON ICIN KONSANTRE SOLUSYONFerric chloride (5.4 mg/10mL) + Chromic chloride (53.3 mcg/10mL) + Cupric Chloride (1.02 mg/10mL) + Manganese chloride (198 mcg/10mL) + Potassium Iodide (166 mcg/10mL) + Sodium selenite (173 mcg/10mL) + Sodium fluoride (2.1 mg/10mL) + Sodium molybdate (48.5 mcg/10mL) + Zinc chloride (10.5 mg/10mL)Injection, solutionIntravenousFRESENİUS KABİ İLAÇ SAN. VE TİC. LTD. ŞTİ.2016-09-062022-11-10Turkey flag

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of inorganic compounds known as transition metal chlorides. These are inorganic compounds in which the largest halogen atom is Chlorine, and the heaviest metal atom is a transition metal.
Kingdom
Inorganic compounds
Super Class
Mixed metal/non-metal compounds
Class
Transition metal salts
Sub Class
Transition metal chlorides
Direct Parent
Transition metal chlorides
Alternative Parents
Inorganic chloride salts
Substituents
Inorganic chloride salt / Inorganic salt / Transition metal chloride
Molecular Framework
Not Available
External Descriptors
iron coordination entity (CHEBI:30808)
Affected organisms
Not Available

Chemical Identifiers

UNII
U38V3ZVV3V
CAS number
7705-08-0
InChI Key
RBTARNINKXHZNM-UHFFFAOYSA-K
InChI
InChI=1S/3ClH.Fe/h3*1H;/q;;;+3/p-3
IUPAC Name
trichloroiron
SMILES
Cl[Fe](Cl)Cl

References

General References
Not Available
ChemSpider
22792
RxNav
24898
ChEBI
30808
ChEMBL
CHEMBL2219605
Wikipedia
Iron(III)_chloride

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Solution, concentrateIntravenous
Injection, solutionIntravenous
Injection, solution, concentrateIntravenous
InjectionIntravenous5.33 mcg/ml
Injection, solutionIntravenous drip
SolutionIntravenous5.33 mcg/ml
SolutionIntravenous
Injection, solutionParenteral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility7.29 mg/mLALOGPS
logP2.06ALOGPS
logP2.3Chemaxon
logS-1.4ALOGPS
Physiological Charge0Chemaxon
Hydrogen Acceptor Count0Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area0 Å2Chemaxon
Rotatable Bond Count0Chemaxon
Refractivity18.41 m3·mol-1Chemaxon
Polarizability10.16 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at October 10, 2019 15:54 / Updated at March 03, 2021 21:58