Ammonium carbonate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Ammonium carbonate is an expectorant indicated to treat a cough and phlegm.

Generic Name
Ammonium carbonate
DrugBank Accession Number
DB15926
Background

Not Available

Type
Small Molecule
Groups
Approved, Experimental
Structure
Weight
Average: 96.086
Monoisotopic: 96.053492126
Chemical Formula
CH8N2O3
Synonyms
  • Carbonic acid, diammonium salt
  • Crystal ammonia
  • Diammonium carbonate
External IDs
  • 208-058-0
  • E 503(I)
  • E-503(I)
  • INS 503(I)
  • INS-503(I)

Pharmacology

Indication

Not Available

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Used in combination for symptomatic treatment ofCoughingCombination Product in combination with: Glycyrrhiza glabra (DB14312)••• •••••••••••
Used in combination for therapyExcess mucus or phlegmCombination Product in combination with: Glycyrrhiza glabra (DB14312)••• •••••••••••
Associated Therapies
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Bronchozone Cough Syrup CertifiedAmmonium carbonate (30 mg / mL) + Ammonium chloride (42 mg / mL) + Glycyrrhiza glabra (0.012 mL / mL) + Levomenthol (0.31 mg / mL) + Polygala senega root (0.015 mL / mL)SyrupOralD.C. Labs Limited1951-12-312003-07-11Canada flag
Esprit D'ammoniaque AromatiqueAmmonium carbonate (4 g / 100 mL) + Ammonia (1.9 g / 100 mL)LiquidNasal; Respiratory (inhalation)Lab Valmo EnregistrÉ, Division Of Technilab Inc.1991-12-311996-09-09Canada flag
ยาแก้ไอขับเสมหะผสมชะเอมAmmonium carbonate (20 MG/5ML) + Glycyrrhiza glabra (0.25 ML/5ML)Solutionองค์การเภสัชกรรม2012-08-07Not applicableThailand flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
PDP691CN28
CAS number
506-87-6
InChI Key
PRKQVKDSMLBJBJ-UHFFFAOYSA-N
InChI
InChI=1S/CH2O3.2H3N/c2-1(3)4;;/h(H2,2,3,4);2*1H3
IUPAC Name
diammonium carbonate
SMILES
[NH4+].[NH4+].[O-]C([O-])=O

References

General References
  1. FDA Thailand: AMMONIUM CARBONATE AND GLYCYRRHIZA MIXTURE, oral solution [Link]
ChemSpider
10048
RxNav
1310190
ChEMBL
CHEMBL2105849
Wikipedia
Ammonium_carbonate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SyrupOral
LiquidNasal; Respiratory (inhalation)
Solution
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility756.0 mg/mLALOGPS
logP-0.53ALOGPS
logP0.25Chemaxon
logS0.9ALOGPS
pKa (Strongest Acidic)3.5Chemaxon
Physiological Charge-1Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area63.19 Å2Chemaxon
Rotatable Bond Count0Chemaxon
Refractivity31.17 m3·mol-1Chemaxon
Polarizability3.52 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-98.20793
predicted
DeepCCS 1.0 (2019)
[M+H]+101.00058
predicted
DeepCCS 1.0 (2019)
[M+Na]+109.81909
predicted
DeepCCS 1.0 (2019)

Drug created at November 24, 2020 14:27 / Updated at May 07, 2021 21:08