Reaction: 4-Hydroxytamoxifen to 1 product

Reaction
Reaction type
O-glucruonidation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Whirl-Carrillo M, McDonagh EM, Hebert JM, Gong L, Sangkuhl K, Thorn CF, Altman RB, Klein TE: Pharmacogenomics knowledge for personalized medicine. Clin Pharmacol Ther. 2012 Oct;92(4):414-7. doi: 10.1038/clpt.2012.96. [PubMed:22992668]
Enzymes
EnzymeKmVmaxRole
UDP-glucuronosyltransferase 1-8Not AvailableNot Availableconfirmed
UDP-glucuronosyltransferase 1-10Not AvailableNot Availableconfirmed
UDP-glucuronosyltransferase 2B15Not AvailableNot Availableconfirmed
UDP-glucuronosyltransferase 1-4Not AvailableNot Availableconfirmed
UDP-glucuronosyltransferase 2B7Not AvailableNot Availableconfirmed