Reaction: Ethinylestradiol to 1 product
- Reaction
- Reaction type
- sulfation
- Direction
- Major circulating metabolite?
- Yes
- Spontaneous?
- No
- Activity
- unknown
- References
- Schrag ML, Cui D, Rushmore TH, Shou M, Ma B, Rodrigues AD: Sulfotransferase 1E1 is a low km isoform mediating the 3-O-sulfation of ethinyl estradiol. Drug Metab Dispos. 2004 Nov;32(11):1299-303. doi: 10.1124/dmd.32.11.. [Article]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role Estrogen sulfotransferase Not Available Not Available confirmed Sulfotransferase 1A3/1A4 Not Available Not Available confirmed