Reaction: Dextrorphan to 1 product

Reaction
Dextrorphan
DB14682
Dextrorphan O-glucuronide
DBMET00595
Reaction type
glucuronidation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
UDP-glucuronosyltransferases (UGTs)Not AvailableNot Availableimplied
UDP-glucuronosyltransferase 2B4Not AvailableNot Availableconfirmed
UDP-glucuronosyltransferase 2B7Not AvailableNot Availableconfirmed
UDP-glucuronosyltransferase 2B15Not AvailableNot Availableconfirmed
UDP-glucuronosyltransferase 2B17Not AvailableNot Availableconfirmed