Reaction: Idelalisib to 1 product

Reaction
Idelalisib
DB09054
GS-563117
DBMET01387
Reaction type
Not Available
Direction
Major circulating metabolite?
Yes
Spontaneous?
No
Activity
inactive
References
  1. Jin F, Robeson M, Zhou H, Moyer C, Wilbert S, Murray B, Ramanathan S: Clinical drug interaction profile of idelalisib in healthy subjects. J Clin Pharmacol. 2015 Aug;55(8):909-19. doi: 10.1002/jcph.495. Epub 2015 May 6. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Aldehyde oxidaseNot AvailableNot Availableconfirmed
Cytochrome P450 3A SubfamilyNot AvailableNot Availableconfirmed