Reaction: Oxcarbazepine to 2 products

Reaction
Oxcarbazepine
DBMET01409
    Eslicarbazepine
    DBMET02148
    R-licarbazepine
    DBMET01410
    Reaction type
    reduction
    Direction
    Major circulating metabolite?
    No
    Spontaneous?
    No
    Activity
    active
    References
    1. Bialer M, White HS: Key factors in the discovery and development of new antiepileptic drugs. Nat Rev Drug Discov. 2010 Jan;9(1):68-82. doi: 10.1038/nrd2997. [Article]
    2. Banach M, Borowicz KK, Czuczwar SJ: Pharmacokinetic/pharmacodynamic evaluation of eslicarbazepine for the treatment of epilepsy. Expert Opin Drug Metab Toxicol. 2015 Apr;11(4):639-48. doi: 10.1517/17425255.2015.1021686. Epub 2015 Mar 5. [Article]
    Comments
    Not Available
    Enzymes
    Not Available