Reaction: Sennidin A to 1 product

Reaction
Reaction type
hydrolysis
Direction
Major circulating metabolite?
Yes
Spontaneous?
No
Activity
active
References
  1. Kon R, Ikarashi N, Nagoya C, Takayama T, Kusunoki Y, Ishii M, Ueda H, Ochiai W, Machida Y, Sugita K, Sugiyama K: Rheinanthrone, a metabolite of sennoside A, triggers macrophage activation to decrease aquaporin-3 expression in the colon, causing the laxative effect of rhubarb extract. J Ethnopharmacol. 2014 Feb 27;152(1):190-200. doi: 10.1016/j.jep.2013.12.055. Epub 2014 Jan 8. [PubMed:24412547]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Beta-glucosidaseNot AvailableNot Availableimplied