Reaction: Dexlansoprazole to 1 product

Reaction
Dexlansoprazole
DB05351
5-Hydroxy dexlansoprazole
DBMET01494
Reaction type
5-hydroxylation
Direction
Major circulating metabolite?
Yes
Spontaneous?
No
Activity
inactive
References
  1. Grabowski B, Lee RD: Absorption, distribution, metabolism and excretion of [14C]dexlansoprazole in healthy male subjects. Clin Drug Investig. 2012 May 1;32(5):319-32. doi: 10.2165/11630930-000000000-00000. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 2C19Not AvailableNot Availableconfirmed