Reaction: Coumarin to 1 product
- Reaction
- Reaction type
- Ring epoxidation
- Direction
- Major circulating metabolite?
- No
- Spontaneous?
- No
- Activity
- unknown
- References
- Born SL, Caudill D, Fliter KL, Purdon MP: Identification of the cytochromes P450 that catalyze coumarin 3,4-epoxidation and 3-hydroxylation. Drug Metab Dispos. 2002 May;30(5):483-7. [Article]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role Cytochrome P450 1A1 Not Available Not Available implied Cytochrome P450 1A2 Not Available Not Available implied Cytochrome P450 2E1 Not Available Not Available implied
