Reaction: Phenacetin to 1 product
- Reaction
- Reaction type
- O-dealkylation
- Direction
- Major circulating metabolite?
- No
- Spontaneous?
- No
- Activity
- unknown
- References
- Rendic S: Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metab Rev. 2002 Feb-May;34(1-2):83-448. [Article]
- Wang B, Zhou SF: Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. Curr Med Chem. 2009;16(31):4066-218. [Article]
- Venkatakrishnan K, von Moltke LL, Greenblatt DJ: Human cytochromes P450 mediating phenacetin O-deethylation in vitro: validation of the high affinity component as an index of CYP1A2 activity. J Pharm Sci. 1998 Dec;87(12):1502-7. [Article]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role Cytochrome P450 1A1 Not Available Not Available implied Cytochrome P450 1A2 Not Available Not Available implied Cytochrome P450 2E1 Not Available Not Available implied Cytochrome P450 2D6 Not Available Not Available implied Cytochrome P450 2C19 Not Available Not Available implied Cytochrome P450 2C9 Not Available Not Available implied Cytochrome P450 2A6 Not Available Not Available implied
