Reaction: Bufuralol to 1 product

Reaction
Reaction type
Aromatic hydroxylation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Brown CM, Reisfeld B, Mayeno AN: Cytochromes P450: a structure-based summary of biotransformations using representative substrates. Drug Metab Rev. 2008;40(1):1-100. doi: 10.1080/03602530802309742 . [Article]
  2. Yamazaki H, Guo Z, Persmark M, Mimura M, Inoue K, Guengerich FP, Shimada T: Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes. Mol Pharmacol. 1994 Sep;46(3):568-77. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 1A2Not AvailableNot Availableimplied
Cytochrome P450 2D6Not AvailableNot Availableimplied