Reaction: Erlotinib to 1 product

Reaction
Reaction type
O-dealkylation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Wang B, Zhou SF: Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. Curr Med Chem. 2009;16(31):4066-218. [PubMed:19754423]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 3A4Not AvailableNot Availableimplied
Cytochrome P450 3A5Not AvailableNot Availableimplied
Cytochrome P450 1A1Not AvailableNot Availableimplied
Cytochrome P450 1A2Not AvailableNot Availableimplied