Reaction: vemurafenib intermediary metabolite to 1 product

Reaction
Reaction type
hydrolysis
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Goldinger SM, Rinderknecht J, Dummer R, Kuhn FP, Yang KH, Lee L, Ayala RC, Racha J, Geng W, Moore D, Liu M, Joe AK, Bazan SP, Grippo JF: A single-dose mass balance and metabolite-profiling study of vemurafenib in patients with metastatic melanoma. Pharmacol Res Perspect. 2015 Mar;3(2):e00113. doi: 10.1002/prp2.113. [PubMed:25729580]
Comments
Not Available
Enzymes
Not Available