Reaction: Nalmefene to 1 product
- Reaction
- Reaction type
- O-glucuronidation
- Direction
- Major circulating metabolite?
- Yes
- Spontaneous?
- No
- Activity
- inactive
- References
- Dixon R, Hsiao J, Hsu HB, Smulkowski M, Tze-Ming-Chan, Pramanik B, Morton J: Isolation of a novel morphinan 3-O-diglucuronide metabolite from dog urine. Pharm Res. 1989 Jan;6(1):28-32. [Article]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role UDP-glucuronosyltransferase 2B7 Not Available Not Available confirmed UDP-glucuronosyltransferase 1-3 Not Available Not Available confirmed UDP-glucuronosyltransferase 1-8 Not Available Not Available confirmed