Reaction: Benzydamine to 1 product

Reaction
Reaction type
N-demethylation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Taniguchi-Takizawa T, Shimizu M, Kume T, Yamazaki H: Benzydamine N-oxygenation as an index for flavin-containing monooxygenase activity and benzydamine N-demethylation by cytochrome P450 enzymes in liver microsomes from rats, dogs, monkeys, and humans. Drug Metab Pharmacokinet. 2015 Feb;30(1):64-9. doi: 10.1016/j.dmpk.2014.09.006. Epub 2014 Oct 5. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 2D6Not AvailableNot Availableimplied