Reaction: Arbutin to 2 products

Reaction
Arbutin
DB11217
    D-glucose
    DB01914
    Hydroquinone
    DB09526
    Reaction type
    hydrolysis
    Direction
    Major circulating metabolite?
    Yes
    Spontaneous?
    Yes
    Activity
    active
    References
    1. Quintus J, Kovar KA, Link P, Hamacher H: Urinary excretion of arbutin metabolites after oral administration of bearberry leaf extracts. Planta Med. 2005 Feb;71(2):147-52. doi: 10.1055/s-2005-837782. [Article]
    2. Schindler G, Patzak U, Brinkhaus B, von Niecieck A, Wittig J, Krahmer N, Glockl I, Veit M: Urinary excretion and metabolism of arbutin after oral administration of Arctostaphylos uvae ursi extract as film-coated tablets and aqueous solution in healthy humans. J Clin Pharmacol. 2002 Aug;42(8):920-7. [Article]
    3. Chemical Information Review Document for Arbutin [CAS No. 497-76-7] for Arbutin and Extracts from Arctostaphylos uva-ursi [File]
    Comments
    Not Available
    Enzymes
    Not Available