Reaction: Tafenoquine to 1 product

Reaction
Tafenoquine
DB06608
5,6-ortho-quinone
DBMET02126
Reaction type
hydrolysis
Direction
Major circulating metabolite?
Yes
Spontaneous?
No
Activity
active
References
  1. Ebstie YA, Abay SM, Tadesse WT, Ejigu DA: Tafenoquine and its potential in the treatment and relapse prevention of Plasmodium vivax malaria: the evidence to date. Drug Des Devel Ther. 2016 Jul 26;10:2387-99. doi: 10.2147/DDDT.S61443. eCollection 2016. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 2D6Not AvailableNot Availableconfirmed