Reaction: Loteprednol etabonate to 1 product

Reaction
Loteprednol etabonate
DB14596
Δ1-cortienic acid etabonate (PJ-91)
DBMET02133
Reaction type
hydrolysis
Direction
Major circulating metabolite?
Yes
Spontaneous?
No
Activity
inactive
References
  1. Samir A, Bodor N, Imai T: Identification of esterase involved in the metabolism of two corticosteroid soft drugs. Biochem Pharmacol. 2017 Mar 1;127:82-89. doi: 10.1016/j.bcp.2016.12.010. Epub 2016 Dec 22. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Serum paraoxonase/arylesterase 1Not AvailableNot Availableimplied