Reaction: Lisdexamfetamine to 2 products
- Reaction
- Reaction type
- hydrolysis
- Direction
- Major circulating metabolite?
- Yes
- Spontaneous?
- No
- Activity
- active
- References
- Goodman DW: Lisdexamfetamine dimesylate (vyvanse), a prodrug stimulant for attention-deficit/hyperactivity disorder. P T. 2010 May;35(5):273-87. [Article]
- Krishnan SM, Pennick M, Stark JG: Metabolism, distribution and elimination of lisdexamfetamine dimesylate: open-label, single-centre, phase I study in healthy adult volunteers. Clin Drug Investig. 2008;28(12):745-55. doi: 10.2165/0044011-200828120-00002. [Article]
- FDA Approved Drug Products: VYVANSE (lisdexamfetamine dimesylate) capsules and chewable tablets, for oral use, CII (January 2022) [Link]
- Comments
- Not Available
- Enzymes
- Not Available