Reaction: Milnacipran to 1 product

Reaction
Milnacipran
DB04896
N-Desethyl milnacipran
DBMET02295
Reaction type
desethylation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Li F, Chin C, Wangsa J, Ho J: Excretion and metabolism of milnacipran in humans after oral administration of milnacipran hydrochloride. Drug Metab Dispos. 2012 Sep;40(9):1723-35. doi: 10.1124/dmd.112.045120. Epub 2012 May 31. [Article]
  2. Fetzima (levomilnacipran extended-release capsules) Canadian Product Monograph [File]
  3. Fetzima (levomilnacipran) FDA Label [File]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 3A4Not AvailableNot Availableimplied
Cytochrome P450 2C8Not AvailableNot Availableimplied
Cytochrome P450 2C19Not AvailableNot Availableimplied
Cytochrome P450 2D6Not AvailableNot Availableimplied
Cytochrome P450 2J2Not AvailableNot Availableimplied