Reaction: Tamoxifen to 1 product

Reaction
Reaction type
hydoxylation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014]
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 3A4Not AvailableNot Availableconfirmed
Cytochrome P450 3A5Not AvailableNot Availableconfirmed
Cytochrome P450 2C19Not AvailableNot Availableconfirmed
Cytochrome P450 2C9Not AvailableNot Availableconfirmed
Cytochrome P450 2D6Not AvailableNot Availableconfirmed
Cytochrome P450 2B6Not AvailableNot Availableconfirmed
Cytochrome P450 1B1Not AvailableNot Availableimplied