Reaction: Deflazacort to 1 product

Reaction
Deflazacort
DB11921
21-Deflazacort
DBMET02573
Reaction type
deacetylation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
active
References
  1. Deshmukh R, Sharma L, Tekade M, Kesharwani P, Trivedi P, Tekade RK: Force degradation behavior of glucocorticoid deflazacort by UPLC: isolation, identification and characterization of degradant by FTIR, NMR and mass analysis. J Biomed Res. 2016 Mar;30(2):149-161. doi: 10.7555/JBR.30.20150074. Epub 2016 Feb 20. [Article]
  2. Calcort 6mg tablets, Medicines UK [Link]
  3. FDA Approved Drug Products: Emflaza (deflazacort) tablets [Link]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Liver esterasesNot AvailableNot Availableconfirmed