Reaction: Diclofenac to 1 product

Reaction
Diclofenac
DB00586
    diclofenac o-imine methine
    DBMET02617
    Reaction type
    oxidative decarboxylation
    Direction
    Major circulating metabolite?
    No
    Spontaneous?
    No
    Activity
    unknown
    References
    1. Boerma JS, Vermeulen NP, Commandeur JN: One-electron oxidation of diclofenac by human cytochrome P450s as a potential bioactivation mechanism for formation of 2'-(glutathion-S-yl)-deschloro-diclofenac. Chem Biol Interact. 2014 Jan 25;207:32-40. doi: 10.1016/j.cbi.2013.11.001. Epub 2013 Nov 15. [Article]
    Comments
    Not Available
    Enzymes
    Not Available