Reaction: Donepezil to 1 product

Reaction
Reaction type
hydroxylation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Tiseo PJ, Foley K, Friedhoff LT: An evaluation of the pharmacokinetics of donepezil HCl in patients with moderately to severely impaired renal function. Br J Clin Pharmacol. 1998 Nov;46 Suppl 1:56-60. doi: 10.1046/j.1365-2125.1998.0460s1056.x. [PubMed:9839768]
  2. Cacabelos R: Donepezil in Alzheimer's disease: From conventional trials to pharmacogenetics. Neuropsychiatr Dis Treat. 2007 Jun;3(3):303-33. [PubMed:19300564]
Comments
Not Available
Enzymes
Not Available