Reaction: Loratadine to 1 product
- Reaction
- Reaction type
- hydoxylation
- Direction
- Major circulating metabolite?
- No
- Spontaneous?
- No
- Activity
- unknown
- References
- Aratyn-Schaus Y, Ramanathan R: Advances in high-resolution MS and hepatocyte models solve a long-standing metabolism challenge: the loratadine story. Bioanalysis. 2016 Aug;8(16):1645-62. doi: 10.4155/bio-2016-0094. Epub 2016 Jul 27. [Article]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role Cytochrome P450 1A1 Not Available Not Available implied Cytochrome P450 2B6 Not Available Not Available implied Cytochrome P450 2C8 Not Available Not Available implied Cytochrome P450 2C9 Not Available Not Available implied Cytochrome P450 2C19 Not Available Not Available implied Cytochrome P450 2D6 Not Available Not Available implied Cytochrome P450 3A4 Not Available Not Available implied Cytochrome P450 3A5 Not Available Not Available implied