Reaction: Umifenovir to 1 product

Reaction
Umifenovir
DB13609
Arbidol M5 metabolite
DBMET03044
Reaction type
N-demethylation; sulfoxidation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Deng P, Zhong D, Yu K, Zhang Y, Wang T, Chen X: Pharmacokinetics, metabolism, and excretion of the antiviral drug arbidol in humans. Antimicrob Agents Chemother. 2013 Apr;57(4):1743-55. doi: 10.1128/AAC.02282-12. Epub 2013 Jan 28. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 3A4Not AvailableNot Availableimplied
Dimethylaniline monooxygenase [N-oxide-forming] 1Not AvailableNot Availableimplied
Dimethylaniline monooxygenase [N-oxide-forming] 3Not AvailableNot Availableimplied