Reaction: Valproic acid to 1 product
- Reaction
- Reaction type
- O-glucuronidation
- Direction
- Major circulating metabolite?
- No
- Spontaneous?
- No
- Activity
- unknown
- References
- Thorn CF, Klein TE, Altman RB: PharmGKB: the Pharmacogenomics Knowledge Base. Methods Mol Biol. 2013;1015:311-20. doi: 10.1007/978-1-62703-435-7_20. [Article]
- Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [Article]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role UDP-glucuronosyltransferase 1-9 Not Available Not Available confirmed UDP-glucuronosyltransferase 1-3 Not Available Not Available confirmed UDP-glucuronosyltransferase 1-4 Not Available Not Available confirmed UDP-glucuronosyltransferase 1-10 Not Available Not Available confirmed UDP-glucuronosyltransferase 1-8 Not Available Not Available confirmed UDP-glucuronosyltransferase 1-6 Not Available Not Available confirmed UDP-glucuronosyltransferase 2B7 Not Available Not Available confirmed UDP-glucuronosyltransferase 2B15 Not Available Not Available confirmed