Reaction: Valproic acid to 1 product

Reaction
Reaction type
O-glucuronidation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Thorn CF, Klein TE, Altman RB: PharmGKB: the Pharmacogenomics Knowledge Base. Methods Mol Biol. 2013;1015:311-20. doi: 10.1007/978-1-62703-435-7_20. [PubMed:23824865]
  2. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
UDP-glucuronosyltransferase 1-9Not AvailableNot Availableconfirmed
UDP-glucuronosyltransferase 1-3Not AvailableNot Availableconfirmed
UDP-glucuronosyltransferase 1-4Not AvailableNot Availableconfirmed
UDP-glucuronosyltransferase 1-10Not AvailableNot Availableconfirmed
UDP-glucuronosyltransferase 1-8Not AvailableNot Availableconfirmed
UDP-glucuronosyltransferase 1-6Not AvailableNot Availableconfirmed
UDP-glucuronosyltransferase 2B7Not AvailableNot Availableconfirmed
UDP-glucuronosyltransferase 2B15Not AvailableNot Availableconfirmed