Reaction: Clobazam to 1 product

Reaction
Clobazam
DB00349
4'-hydroxyclobazam
DBMET00743
Reaction type
4'-hydroxylation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
inactive
References
  1. Giraud C, Tran A, Rey E, Vincent J, Treluyer JM, Pons G: In vitro characterization of clobazam metabolism by recombinant cytochrome P450 enzymes: importance of CYP2C19. Drug Metab Dispos. 2004 Nov;32(11):1279-86. [Article]
  2. FDA Approved Drug Products: ONFI® (clobazam) tablets, for oral use, CIV [Link]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 2C18Not AvailableNot Availableconfirmed
Cytochrome P450 2C19Not AvailableNot Availableconfirmed