Reaction: Hydromorphone to 1 product
- Reaction
- Reaction type
- glucuronidation
- Direction
- Major circulating metabolite?
- Yes
- Spontaneous?
- No
- Activity
- active
- References
- Abi-Aad KR, Derian A: Hydromorphone . [Article]
- Overholser BR, Foster DR: Opioid pharmacokinetic drug-drug interactions. Am J Manag Care. 2011 Sep;17 Suppl 11:S276-87. [Article]
- Gudin J: Opioid therapies and cytochrome p450 interactions. J Pain Symptom Manage. 2012 Dec;44(6 Suppl):S4-14. doi: 10.1016/j.jpainsymman.2012.08.013. [Article]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role UDP-glucuronosyltransferase 1-3 Not Available Not Available confirmed UDP-glucuronosyltransferase 2B7 Not Available Not Available confirmed