Reaction: Ropinirole to 3 products

Reaction
Ropinirole
DB00268
N-despropyl hydroxy metabolites
DBMET02235
N-despropyl ropinirole
DBMET00940
carboxylic acid
DBMET02236
Reaction type
N-despropylation; hydroxylation
Direction
Not Available
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Kushida CA: Ropinirole for the treatment of restless legs syndrome. Neuropsychiatr Dis Treat. 2006 Dec;2(4):407-19. [Article]
  2. FDA label, requip [File]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 1A2Not AvailableNot Availableimplied