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Substrate
Enzyme
Products
Clear
Metoclopramide
DB01233
Not Available
Conjugated metabolite, Metoclopramide
Details
Metoprolol
DB00264
Cytochrome P450 2C19
Deisopropylmetoprolol
Details
Metoprolol
DB00264
Cytochrome P450 2D6
alpha-Hydroxymetoprolol
Details
Metoprolol
DB00264
Cytochrome P450 2D6
/
Cytochrome P450 3A4
O-Demethylmetoprolol
Details
Metronidazole
DB00916
Cytochrome P450 3A4
/
Cytochrome P450 2A6
/
Cytochrome P450 3A5
/
Cytochrome P450 3A7
2-hydroxymetronidazole
Details
Metyrapone
DB01011
Not Available
Metyrapol
Details
Mexiletine
DB00379
Cytochrome P450 1A2
/
Cytochrome P450 2D6
p-hydroxymexiletine
Details
Mexiletine
DB00379
Cytochrome P450 1A2
/
Cytochrome P450 2D6
2-hydroxymexiletine
Details
Mianserin
DB06148
Cytochrome P450 3A4
(R)-mianserin, N-oxide
Details
Mianserin
DB06148
Cytochrome P450 2B6
/
Cytochrome P450 3A4
/
Cytochrome P450 2C19
/
Cytochrome P450 1A2
Desmethylmianserin
Details
Mianserin
DB06148
Cytochrome P450 2D6
/
Cytochrome P450 1A2
/
Cytochrome P450 3A4
/
Cytochrome P450 2B6
(R)-mianserin, N-Desmethyl
Details
Mianserin
DB06148
Cytochrome P450 2D6
/
Cytochrome P450 3A4
(R)-mianserin, 8-hydroxy
Details
Mianserin
DB06148
Cytochrome P450 2D6
/
Cytochrome P450 2B6
/
Cytochrome P450 3A4
8-Hydroxymianserin
Details
Mianserin
DB06148
Cytochrome P450 3A4
/
Cytochrome P450 1A2
Mianserin N-oxide
Details
Midazolam
DB00683
Cytochrome P450 3A4
1-hydroxymidazolam
Details
Midazolam
DB00683
UDP-glucuronosyltransferase 2B7
Midazolam-N-glucuronide
Details
Midazolam
DB00683
Cytochrome P450 3A4
/
Cytochrome P450 3A5
4-hydroxymidazolam
Details
Midodrine
DB00211
Not Available
desglymidodrine
Details
Midostaurin
DB06595
Cytochrome P450 3A4
CGP 52421
Details
Midostaurin
DB06595
Cytochrome P450 3A4
CGP 62221
Details
Mifepristone
DB00834
Cytochrome P450 3A4
Monodemethylated mifepristone
Details
Mifepristone
DB00834
Cytochrome P450 3A4
17alpha-hydroxymifepristone
Details
Milnacipran
DB04896
Cytochrome P450 3A4
/
Cytochrome P450 2C8
/
Cytochrome P450 2C19
/
Cytochrome P450 2D6
/
Cytochrome P450 2J2
N-Desethyl milnacipran
Details
Milnacipran
DB04896
Not Available
Milnacipran carbamic acid
Details
Milnacipran carbamic acid
DBMET02300
Not Available
Milnacipran carbamoyl O-glucuronide
Details
Miltefosine
DB09031
Phospholipase D1
Choline
Details
Minaprine
DB00805
Cytochrome P450 2D6
4-Hydroxyminaprine
Details
Minocycline
DB01017
Not Available
Minocycline M3 Metabolite
Details
Minocycline
DB01017
Not Available
9-hydroxyminocycline
Details
Minocycline
DB01017
Not Available
Minocycline M7 Metabolite
Details
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