Cysteamine hydrochlorideProduct ingredient for Cysteamine

Name
Cysteamine hydrochloride
Drug Entry
Cysteamine

Cysteamine is a radiation-protective agent that oxidizes in air to form cystamine. It can be given intravenously or orally to treat radiation sickness. The bitartrate and hydrochloride salt forms are indicated for the treatment of neuropathic cystinosis in patients 6 years old and older. Cysteamine is marketed under several brand names such as Cystaran, Procysbi, and Cystagon.

Accession Number
DBSALT000033
Structure
Thumb
Synonyms
Cysteamine HCl
UNII
IF1B771SVB
CAS Number
156-57-0
Weight
Average: 113.61
Monoisotopic: 113.006597658
Chemical Formula
C2H8ClNS
InChI Key
OGMADIBCHLQMIP-UHFFFAOYSA-N
InChI
InChI=1S/C2H7NS.ClH/c3-1-2-4;/h4H,1-3H2;1H
IUPAC Name
2-aminoethane-1-thiol hydrochloride
SMILES
Cl.NCCS
External Links
PubChem Compound
9082
ChemSpider
8729
ChEBI
805121
ChEMBL
CHEMBL1256137
Wikipedia
Cysteamine
Predicted Properties
PropertyValueSource
Water Solubility23.5 mg/mLALOGPS
logP0.01ALOGPS
logP-0.42ChemAxon
logS-0.52ALOGPS
pKa (Strongest Acidic)9.42ChemAxon
pKa (Strongest Basic)10.4ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count1ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area26.02 Å2ChemAxon
Rotatable Bond Count1ChemAxon
Refractivity22.39 m3·mol-1ChemAxon
Polarizability8.65 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon