Pseudoephedrine sulfateProduct ingredient for Pseudoephedrine
- Name
- Pseudoephedrine sulfate
- Drug Entry
- Pseudoephedrine
Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.1,2 Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889.2 The decongestant effect of pseudoephedrine was described in dogs in 1927.2
- Accession Number
- DBSALT000150
- Structure
- Synonyms
- Pseudoephedrine sulfate
- External IDs
- Sch 4855
- UNII
- Y9DL7QPE6B
- CAS Number
- 7460-12-0
- Weight
- Average: 428.54
Monoisotopic: 428.198107932 - Chemical Formula
- C20H32N2O6S
- InChI Key
- CAVQBDOACNULDN-NRCOEFLKSA-N
- InChI
- InChI=1S/2C10H15NO.H2O4S/c2*1-8(11-2)10(12)9-6-4-3-5-7-9;1-5(2,3)4/h2*3-8,10-12H,1-2H3;(H2,1,2,3,4)/t2*8-,10+;/m00./s1
- IUPAC Name
- bis((1S,2S)-2-(methylamino)-1-phenylpropan-1-ol); sulfuric acid
- SMILES
- OS(O)(=O)=O.CN[C@@H](C)[C@@H](O)C1=CC=CC=C1.CN[C@@H](C)[C@@H](O)C1=CC=CC=C1
- External Links
- PubChem Compound
- 62945
- ChemSpider
- 7978435
- ChEBI
- 774851
- ChEMBL
- CHEMBL3989855
- Wikipedia
- Pseudoephedrine
- Predicted Properties
Property Value Source Water Solubility 8.26 mg/mL ALOGPS logP 1 ALOGPS logP 1.32 Chemaxon logS -1.3 ALOGPS pKa (Strongest Acidic) 13.89 Chemaxon pKa (Strongest Basic) 9.52 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 32.26 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 49.69 m3·mol-1 Chemaxon Polarizability 18.75 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon