Foscarnet sodiumProduct ingredient for Foscarnet
- Name
- Foscarnet sodium
- Drug Entry
- Foscarnet
An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
- Accession Number
- DBSALT000200
- Structure
Structure for Foscarnet sodium (DBSALT000200)
- Synonyms
- Phosphinecarboxylic acid, 1,1-dihydroxy-, 1-oxide, sodium salt (1:3) / Phosphonoformic acid trisodium salt / Phosphonoformic acid, trisodium salt / Trisodium phosphonoformate
- UNII
- 8C5OQ81LWT
- CAS Number
- 63585-09-1
- Weight
- Average: 191.9508
Monoisotopic: 191.917643647 - Chemical Formula
- CNa3O5P
- InChI Key
- DFHAXXVZCFXGOQ-UHFFFAOYSA-K
- InChI
- InChI=1S/CH3O5P.3Na/c2-1(3)7(4,5)6;;;/h(H,2,3)(H2,4,5,6);;;/q;3*+1/p-3
- IUPAC Name
- trisodium phosphonatoformate
- SMILES
- [Na+].[Na+].[Na+].[O-]C(=O)P([O-])([O-])=O
- External Links
- Predicted Properties
Property Value Source Water Solubility 46.9 mg/mL ALOGPS logP -0.31 ALOGPS logP -0.83 Chemaxon logS -0.61 ALOGPS pKa (Strongest Acidic) -0.096 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 103.32 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 27.67 m3·mol-1 Chemaxon Polarizability 6.83 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon