Fluphenazine hydrochlorideProduct ingredient for Fluphenazine

Show full entry for Fluphenazine
Name
Fluphenazine hydrochloride
Drug Entry
Fluphenazine

A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.

See full entry for Fluphenazine
Accession Number
DBSALT000288  (DBSALT001197)
Structure
Similar Structures
Synonyms
Fluphenazine diHCl / Fluphenazine dihydrochloride / Fluphenazine HCl
External IDs
SQUIBB 4918
UNII
ZOU145W1XL
CAS Number
146-56-5
Weight
Average: 510.443
Monoisotopic: 509.128223252
Chemical Formula
C22H28Cl2F3N3OS
InChI Key
MBHNWCYEGXQEIT-UHFFFAOYSA-N
InChI
InChI=1S/C22H26F3N3OS.2ClH/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29;;/h1-2,4-7,16,29H,3,8-15H2;2*1H
IUPAC Name
2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol dihydrochloride
SMILES
Cl.Cl.OCCN1CCN(CCCN2C3=CC=CC=C3SC3=C2C=C(C=C3)C(F)(F)F)CC1
PubChem Compound
67356
ChemSpider
60687
ChEBI
5126
ChEMBL
CHEMBL1448187
Wikipedia
Fluphenazine
Predicted Properties
PropertyValueSource
Water Solubility0.019 mg/mLALOGPS
logP4.4ALOGPS
logP3.97Chemaxon
logS-4.4ALOGPS
pKa (Strongest Acidic)15.59Chemaxon
pKa (Strongest Basic)7.81Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count4Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area29.95 Å2Chemaxon
Rotatable Bond Count7Chemaxon
Refractivity117.27 m3·mol-1Chemaxon
Polarizability45.07 Å3Chemaxon
Number of Rings4Chemaxon
Bioavailability1Chemaxon
Rule of FiveNoChemaxon
Ghose FilterNoChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleYesChemaxon