Ganciclovir sodiumProduct ingredient for Ganciclovir
- Name
- Ganciclovir sodium
- Drug Entry
- Ganciclovir
An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
- Accession Number
- DBSALT000309
- Structure
- Synonyms
- Not Available
- UNII
- 02L083W284
- CAS Number
- 107910-75-8
- Weight
- Average: 277.2124
Monoisotopic: 277.078698572 - Chemical Formula
- C9H12N5NaO4
- InChI Key
- JJICLMJFIKGAAU-UHFFFAOYSA-M
- InChI
- InChI=1S/C9H13N5O4.Na/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16;/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17);/q;+1/p-1
- IUPAC Name
- sodium 9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-2-imino-3,9-dihydro-2H-purin-6-olate
- SMILES
- [Na+].OCC(CO)OCN1C=NC2=C1NC(=N)N=C2[O-]
- External Links
- PubChem Compound
- 23700083
- ChemSpider
- 54279
- ChEBI
- 774801
- ChEMBL
- CHEMBL1200850
- Wikipedia
- Ganciclovir
- Predicted Properties
Property Value Source Water Solubility 7.95 mg/mL ALOGPS logP -1.5 ALOGPS logP -3.1 Chemaxon logS -1.5 ALOGPS pKa (Strongest Acidic) -6.3 Chemaxon pKa (Strongest Basic) 20.4 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 8 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 138.81 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 82.16 m3·mol-1 Chemaxon Polarizability 23.95 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon