Metronidazole hydrochlorideProduct ingredient for Metronidazole
- Name
- Metronidazole hydrochloride
- Drug Entry
- Metronidazole
Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics.14 It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections.4,5 Metronidazole has been used as an antibiotic for several decades15, with added antiparasitic properties that set it apart from many other antibacterial drugs, allowing it to treat a wide variety of infections. It is available in capsule form, tablet form, and topical form, and suppository preparations for the treatment of various infections.
- Accession Number
- DBSALT000362
- Structure
Structure for Metronidazole hydrochloride (DBSALT000362)
- Synonyms
- Metronidazole HCl
- UNII
- 76JC1633UF
- CAS Number
- 69198-10-3
- Weight
- Average: 207.615
Monoisotopic: 207.041068908 - Chemical Formula
- C6H10ClN3O3
- InChI Key
- FPTPAIQTXYFGJC-UHFFFAOYSA-N
- InChI
- InChI=1S/C6H9N3O3.ClH/c1-5-7-4-6(9(11)12)8(5)2-3-10;/h4,10H,2-3H2,1H3;1H
- IUPAC Name
- 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethan-1-ol hydrochloride
- SMILES
- Cl.CC1=NC=C(N1CCO)N(=O)=O
- External Links
- PubChem Compound
- 68592
- ChemSpider
- 61860
- ChEBI
- 50687
- ChEMBL
- CHEMBL1200869
- Wikipedia
- Metronidazole
- Predicted Properties
Property Value Source Water Solubility 5.92 mg/mL ALOGPS logP -0.15 ALOGPS logP -0.46 Chemaxon logS -1.5 ALOGPS pKa (Strongest Acidic) 15.42 Chemaxon pKa (Strongest Basic) 2.81 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 83.87 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 41.22 m3·mol-1 Chemaxon Polarizability 15.81 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon