Sulfoxone sodiumProduct ingredient for Sulfoxone
- Name
- Sulfoxone sodium
- Drug Entry
- Sulfoxone
Sulfoxone is a water-soluble sulfone used as an antileprosy drug. It has been used with limited success in the treatment of dermatitis herpetiformis.
- Accession Number
- DBSALT000408
- Structure
Structure for Sulfoxone sodium (DBSALT000408)
- Synonyms
- Aldesulfone sodium / Aldesulphone sodium / Diasone sodium / Disodium (sulfonylbis(p-phenyleneimino))dimethanesulfinate
- UNII
- 57OWB0Q221
- CAS Number
- 144-75-2
- Weight
- Average: 448.445
Monoisotopic: 447.98093761 - Chemical Formula
- C14H14N2Na2O6S3
- InChI Key
- AZBNFLZFSZDPQF-UHFFFAOYSA-L
- InChI
- InChI=1S/C14H16N2O6S3.2Na/c17-23(18)9-15-11-1-5-13(6-2-11)25(21,22)14-7-3-12(4-8-14)16-10-24(19)20;;/h1-8,15-16H,9-10H2,(H,17,18)(H,19,20);;/q;2*+1/p-2
- IUPAC Name
- disodium [(4-{4-[(sulfinatomethyl)amino]benzenesulfonyl}phenyl)amino]methanesulfinate
- SMILES
- [Na+].[Na+].[O-]S(=O)CNC1=CC=C(C=C1)S(=O)(=O)C1=CC=C(NCS([O-])=O)C=C1
- External Links
- PubChem Compound
- 8954
- ChemSpider
- 8610
- ChEBI
- 774531
- ChEMBL
- CHEMBL1200580
- Predicted Properties
Property Value Source Water Solubility 3.19 mg/mL ALOGPS logP 1.79 ALOGPS logP 1.27 Chemaxon logS -2.2 ALOGPS pKa (Strongest Acidic) 1.7 Chemaxon pKa (Strongest Basic) -0.056 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 8 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 138.46 Å2 Chemaxon Rotatable Bond Count 8 Chemaxon Refractivity 94.71 m3·mol-1 Chemaxon Polarizability 38.61 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon