Oxybutynin chlorideProduct ingredient for Oxybutynin
- Name
- Oxybutynin chloride
- Drug Entry
- Oxybutynin
Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients worldwide. Due to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social embarrassment and a poor quality of life.4,5
Oxybutynin, also marketed as Ditropan XL, is an anticholinergic medication used for the relief of overactive bladder symptoms that has been optimized for high levels of safety and efficacy since initial FDA approval in 1975.2,14 This drug relieves undesirable urinary symptoms, increasing the quality of life for patients affected by OAB. It is often used as first-line therapy for OAB.3
- Accession Number
- DBSALT000430
- Structure
Structure for Oxybutynin chloride (DBSALT000430)
- Synonyms
- Oxybutynin HCl / Oxybutynin hydrochloride
- UNII
- L9F3D9RENQ
- CAS Number
- 1508-65-2
- Weight
- Average: 393.947
Monoisotopic: 393.207071602 - Chemical Formula
- C22H32ClNO3
- InChI Key
- SWIJYDAEGSIQPZ-UHFFFAOYSA-N
- InChI
- InChI=1S/C22H31NO3.ClH/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20;/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3;1H
- IUPAC Name
- 4-(diethylamino)but-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate hydrochloride
- SMILES
- Cl.CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)C1=CC=CC=C1
- External Links
- KEGG Drug
- D00722
- PubChem Compound
- 91505
- ChemSpider
- 82626
- ChEBI
- 7857
- ChEMBL
- CHEMBL1133
- Wikipedia
- Oxybutynin
- Predicted Properties
Property Value Source Water Solubility 0.01 mg/mL ALOGPS logP 4.36 ALOGPS logP 4.44 Chemaxon logS -4.6 ALOGPS pKa (Strongest Acidic) 11.53 Chemaxon pKa (Strongest Basic) 8.77 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 49.77 Å2 Chemaxon Rotatable Bond Count 10 Chemaxon Refractivity 105.26 m3·mol-1 Chemaxon Polarizability 41.69 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon