Proparacaine hydrochlorideProduct ingredient for Proparacaine
- Name
- Proparacaine hydrochloride
- Drug Entry
- Proparacaine
Proparacaine is a topical anesthetic drug of the amino ester group. It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt.
- Accession Number
- DBSALT000459
- Structure
- Synonyms
- 2-(diethylamino)ethyl 3-amino-4-propoxybenzoate monohydrochloride / Proparacaine HCl / Proxymetacaine hydrochloride
- UNII
- U96OL57GOY
- CAS Number
- 5875-06-9
- Weight
- Average: 330.85
Monoisotopic: 330.171020447 - Chemical Formula
- C16H27ClN2O3
- InChI Key
- BFUUJUGQJUTPAF-UHFFFAOYSA-N
- InChI
- InChI=1S/C16H26N2O3.ClH/c1-4-10-20-15-8-7-13(12-14(15)17)16(19)21-11-9-18(5-2)6-3;/h7-8,12H,4-6,9-11,17H2,1-3H3;1H
- IUPAC Name
- 2-(diethylamino)ethyl 3-amino-4-propoxybenzoate hydrochloride
- SMILES
- Cl.CCCOC1=C(N)C=C(C=C1)C(=O)OCCN(CC)CC
- External Links
- PubChem Compound
- 22169
- ChemSpider
- 20811
- ChEMBL
- CHEMBL1200464
- Wikipedia
- Proxymetacaine
- Predicted Properties
Property Value Source Water Solubility 1.39 mg/mL ALOGPS logP 2.97 ALOGPS logP 2.6 Chemaxon logS -2.3 ALOGPS pKa (Strongest Basic) 8.96 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 64.79 Å2 Chemaxon Rotatable Bond Count 10 Chemaxon Refractivity 86.04 m3·mol-1 Chemaxon Polarizability 34.55 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon