Cyproheptadine hydrochlorideProduct ingredient for Cyproheptadine
- Name
- Cyproheptadine hydrochloride
- Drug Entry
- Cyproheptadine
Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors.8 It is used primarily to treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation11 and its off-label use in the treatment of serotonin syndrome.2
- Accession Number
- DBSALT000625
- Structure
Structure for Cyproheptadine hydrochloride (DBSALT000625)
- Synonyms
- Cyproheptadine HCl
- UNII
- 0S9323MCT0
- CAS Number
- 969-33-5
- Weight
- Average: 323.859
Monoisotopic: 323.144077416 - Chemical Formula
- C21H22ClN
- InChI Key
- ZPMVNZLARAEGHB-UHFFFAOYSA-N
- InChI
- InChI=1S/C21H21N.ClH/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21;/h2-11H,12-15H2,1H3;1H
- IUPAC Name
- 1-methyl-4-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-ylidene}piperidine hydrochloride
- SMILES
- Cl.CN1CCC(CC1)=C1C2=CC=CC=C2C=CC2=CC=CC=C12
- External Links
- PubChem Compound
- 13770
- ChemSpider
- 13173
- ChEBI
- 59695
- ChEMBL
- CHEMBL1716
- Wikipedia
- Cyproheptadine
- Predicted Properties
Property Value Source Water Solubility 0.0136 mg/mL ALOGPS logP 5.02 ALOGPS logP 4.38 Chemaxon logS -4.3 ALOGPS pKa (Strongest Basic) 8.05 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 3.24 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 105.17 m3·mol-1 Chemaxon Polarizability 34.02 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon