Meperidine hydrochlorideProduct ingredient for Meperidine

Name
Meperidine hydrochloride
Drug Entry
Meperidine

A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.

Accession Number
DBSALT000628  (DBSALT001046)
Structure
Synonyms
Meperidine HCl / Pethidine HCl / Pethidine hydrochloride
External IDs
S 140 / WY 554
UNII
N8E7F7Q170
CAS Number
50-13-5
Weight
Average: 283.794
Monoisotopic: 283.13390666
Chemical Formula
C15H22ClNO2
InChI Key
WCNLCIJMFAJCPX-UHFFFAOYSA-N
InChI
InChI=1S/C15H21NO2.ClH/c1-3-18-14(17)15(9-11-16(2)12-10-15)13-7-5-4-6-8-13;/h4-8H,3,9-12H2,1-2H3;1H
IUPAC Name
ethyl 1-methyl-4-phenylpiperidine-4-carboxylate hydrochloride
SMILES
Cl.CCOC(=O)C1(CCN(C)CC1)C1=CC=CC=C1
PubChem Compound
5750
ChemSpider
5548
ChEBI
31984
ChEMBL
CHEMBL1701
Wikipedia
Pethidine
Predicted Properties
PropertyValueSource
Water Solubility1.11 mg/mLALOGPS
logP2.9ALOGPS
logP2.46Chemaxon
logS-2.4ALOGPS
pKa (Strongest Basic)8.16Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area29.54 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity72.48 m3·mol-1Chemaxon
Polarizability28.24 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon