Hexylcaine hydrochlorideProduct ingredient for Hexylcaine

Name
Hexylcaine hydrochloride
Drug Entry
Hexylcaine

Hexylcaine hydrochloride is also known as cyclaine and osmocaine. It is a short acting local anesthetic that acts through inhibition of sodium channels. Patients experience an overdose may present with headache, tinnitus, numbness and tingling around the mouth and tongue, convulsions, inability to breathe, and decreased heart function. Hexylcaine has been discontinued in the US market.

Accession Number
DBSALT000630
Structure
Thumb
Synonyms
Hexylcaine HCl
UNII
V00NQ7SDYI
CAS Number
532-76-3
Weight
Average: 297.82
Monoisotopic: 297.149556724
Chemical Formula
C16H24ClNO2
InChI Key
MTFCPNHRBINLRQ-UHFFFAOYSA-N
InChI
InChI=1S/C16H23NO2.ClH/c1-13(12-17-15-10-6-3-7-11-15)19-16(18)14-8-4-2-5-9-14;/h2,4-5,8-9,13,15,17H,3,6-7,10-12H2,1H3;1H
IUPAC Name
1-(cyclohexylamino)propan-2-yl benzoate hydrochloride
SMILES
Cl.CC(CNC1CCCCC1)OC(=O)C1=CC=CC=C1
External Links
PubChem Compound
102426
ChemSpider
92504
ChEBI
774666
ChEMBL
CHEMBL1200715
Wikipedia
Hexylcaine
Predicted Properties
PropertyValueSource
Water Solubility0.00971 mg/mLALOGPS
logP3.04ALOGPS
logP3.83ChemAxon
logS-4.4ALOGPS
pKa (Strongest Basic)9.87ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area38.33 Å2ChemAxon
Rotatable Bond Count6ChemAxon
Refractivity76.24 m3·mol-1ChemAxon
Polarizability30.03 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon